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Generic Name: Chlorpheniramine Maleate 4mg
Manufacturer/Distributor: Bio-Pharma Ltd.
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✅ Description:
Indications
Indicated mainly in allergic conditions including urticaria, sensitivity reactions, angioneurotic edema, seasonal hay fever, vasomotor rhinitis, cough, common cold, and motion sickness.
Pharmacology
Chlorpheniramine is an alkylamine antihistamine. It is one of the most potent H1-blocking agents and is generally effective in relatively low doses. Chlorpheniramine is not so prone to produce drowsiness, is readily absorbed from the gastrointestinal tract, metabolized in the liver, and excreted usually mainly as metabolized in the urine.
Dosage & Administration
- Adults: 4 mg 3-4 times daily.
Children:
- Up to 1() year: 1 mg twice daily
- 1-5 years: 1 mg 3-4 times daily
- 6-12 years: 2 mg 3-4 times daily or as directed by the physician
Interaction
Alcohol, CNS depressants, anticholinergic drugs, MAOIs.
Contraindications
There is no definite contraindication to therapy. It should be used with caution in epilepsy, prostatic hypertrophy, glaucoma, and hepatic disease. The ability to drive or operate machinery may be impaired.
Side Effects
Drowsiness, dizziness, headache, psychomotor impairment, urinary retention, dry mouth, blurred vision, gastrointestinal disturbances, and paradoxical stimulation may rarely occur, especially in high dosages or in children.
Pregnancy & Lactation
Pregnancy Category B. Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Precautions & Warnings
Chlorpheniramine may produce mild sedation and it is advised that patients under continuous treatment should avoid operating machinery. Not recommended during pregnancy & lactation.
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